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The Ohio State University Medical Center
Department of Plastic Surgery
http://plasticsurgery.osu.edu/
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Research


Basic Science Research

  • Gene Directed Enzyme Prodrug Therapy in Gene Modified Muscle Flaps using a Synergeneic Tumor in an Immunocompetent Rat Model. (Dr. Ergun Kocak)
  • Gene Directed Enzyme Prodrug Therapy in Gene Modified Muscle Flaps using a Human Xenograft Tumor in an Immunodeficient Mouse Model. (Dr. Ergun Kocak)
  • Acquired Ischemia Resistance in Plastic Surgical Flaps using Delta Opoid Receptor Agonsists in the Rat Model. (Dr. Ergun Kocak) Roessler Scholarship for Medical Student Research.

Translational Research

  • Gene Expression Profiles in Healing and Non-Healing Wounds. Wound tissue is collected, as well as history and medical outcomes data to determine patterns of gene expression in healing versus non-healing wounds. (Dr. Gayle Gordillo)
     
  • Mechanisms Regulating Wound Vascularization-A Pilot study for the Program Project Initiative Grant to obtain preliminary data for a planned P50 Center grant submission to NIH to establish a wound healing Center of Excellence at OSU. (Dr. Gayle Gordillo)
  • Mechanisms Underlying Impaired Diabetic Wound Healing-Looks at the effects of diabetes on macrophage function in wounds. (Dr. Gayle Gordillo, Co-Investigator)
  • The incidence of malnutrition and other risk factors for impaired healing among inpatients with chronic wounds (2007-2009)-ongoing retrospective chart review of patients seen by the inpatient wound consult service. (Dr. Gayle Gordillo)
  • Isolation of cells and proteins from wound fluid in patients treated with VAC dressings. (2006-present)(Dr. Gayle Gordillo)
  • EAGER: Topological Optimization Methods for Designing Patient Specific Large Craniofacial Segmental Bone Replacements. (Dr. Michael Miller and Alok Sutradhar, Ph.D)

Clinical Research

  • Tissue expander related infection and immunization and delayed breast reconstruction
     
  • The role of Vitamin E in wound healing and scar formation
     
  • Aesthetic outcomes in breast reconstruction and abdominal donor morbidity
     
  • Outcomes data on intraoperative fluoroscopic angiography in microsurgery
     
  • Comprehensive modeling of breast and body aesthetics
     
  • Development of an inpatient and outpatient comprehensive wound care center

Application for OSU Medical Students interested in Plastic Surgery Research